CDK7 and esophageal squamous cell carcinoma: Recent findings have indicated that YAP expression was strongly determined by activated transcription, and an obviously attenuated YAP level was observed when repressing CDK7 using minor THZ1 in ESCC.28 To elucidate if CDK7 interacts with YAP in ESCC cells, CDK7 activity was inhibited by THZ1 treatment, and then YAP levels were assessed.