CSF2 and neoplasm: Furthermore, tumor glycolysis can also promote the expression of granulocyte colony-stimulating factor (G-CSF) and granulocyte macrophage colony-stimulating factor (GM-CSF) in triple-negative breast cancer (TNBC) cells, induce the generation of tumor derived myeloid-derived suppressor cells (MDSCs), and affect tumor immune escape and tumor growth [92].