After FDR adjustment (PFDR<0.05), we detected protective effects of four immunophenotypes on schizophrenia: naive CD4+%T cell (maturation stages of T cell panel), HLA DR on CD14−CD16− (monocyte panel), CD33dimHLA DR+CD11b−AC (myeloid cell panel) and activated & resting Treg % CD4 Treg (Treg panel). This evidence concerns the gene CD4 and schizophrenia.