This comparative analysis identified 5 adipocyte (Calm2 - calmodulin-2, Abcg1 - ATP-binding cassette sub-family G member 1, 2610203C22Rik, Ucp2 - uncoupling protein-2, Vps13d - vacuolar protein sorting 13D) and 4 SVF (Slc16a10 - monocarboxylate transporter 10, Abcg1, Cfd - complement factor D, Aff3 - AF4/FMR2 family member 3) genes that were persistently changed by former obesity or undernutrition. Here, AFF3 is linked to obesity due to melanocortin 4 receptor deficiency.