After controlling with other major prognostic factors including age, sex, smoking status, drinking status, tumor location, histology, N stage, tumor stage, CEA level, NSE level, and Cyfra21-1 level, we found that TLMR remained as a significantly independent prognostic predictor for NSCLC after CCRT (aHR, 0.45; 95% CI, 0.24–0.85 for TLMR and aHR, 0.85; 95% CI, 0.49–1.49 for SUVmax (Table 5). This evidence concerns the gene ENO2 and non-small cell lung carcinoma.