In all of the libraries, the reads preferentially mapped to the 3′UTR regions in agreement with known IGF2BP3-binding preferences in cancer cells (Fig. 4A; Hafner et al. 2010; Palanichamy et al. 2016; Huang et al. 2018) and the IGF2BP3 libraries contained on average 2000 times more crosslinked read clusters compared to the IgG control sample (Fig. 4B,C). The gene discussed is IGF2BP3; the disease is cancer.