Several mechanisms were suggested for the function of IGF2BP3 in promoting tumorigenesis in colon cancers including regulation of mRNA localization, translation, and stabilization of oncogenic transcripts (Rivera Vargas et al. 2014; Deforzh et al. 2016; Ennajdaoui et al. 2016; Li et al. 2020). Here, IGF2BP3 is linked to malignant colon neoplasm.