HMGCR and myositis disease: If concomitant proximal muscle weakness is present, a CK and myositis panel, including anti-cN1A (anti cytosolic 5ʹ-nucleotidase 1A), anti-SRP (antibodies against signal recognition particle), anti-HMGCR (antibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase), anti-NXP2 (antinuclear matrix protein 2 antibody), anti-Jo1 (antihistidyl t-RNA synthetase antibody), and antiM2 (anti-mitochondrial M2 antibody) can be considered [4].