Adgrf1, G-protein-coupled receptor 110; STC, standard chow diet; HFD, high-fat diet; NPC, non-parenchymal cell; BW, body weight; GTT, glucose tolerance test; PTT, pyruvate tolerance test; ITT, insulin tolerance test; AUC, area under curve; NC, negative control; HOMA-IR, homeostasis model assessment-estimated insulin resistance. Here, ADGRF1 is linked to Insulin resistance.