To verify the relationship between NEDD4L and KSRP, we knocked down KSRP in Caki-1 and 786-O cells and found that KSRP-KD cells showed increased protein (Fig. 2B) and mRNA (Fig. 2C) expression levels of NEDD4L compared to control ccRCC cells. Here, NEDD4L is linked to nonpapillary renal cell carcinoma.