They contain miR-185, which downregulates suppressor of cytokine signaling 2 (SOCS2), an inhibitor of growth hormone/IGF signaling [69]; and miR-29b-3p, which downregulates A disintegrin and metalloproteinase with thrombospondin 16 (ADAMTS16), blocking myocardial fibrosis and promoting angiogenesis in a rat model of MI [70]. Here, SOCS2 is linked to Myocardial fibrosis.