It could be seen that the best clustering results achieved when 256 MM patients were clustered into two molecular subtypes (k = 2) no matter based on the expression patterns of 27 BCAA metabolism-related genes (cluster 1 = 159, cluster 2 = 97) or 13 LMRG (cluster 1 = 143, cluster 2 = 113) (Fig. 1A and E). Here, ARID4B is linked to Miyoshi myopathy.