Of note, these analyses demonstrated marked redistribution of the cBAF and COMPASS–MLL1/MLL4 complexes on leukemia induction (Fig. 6a and Extended Data Fig. 10b–d), identifying three major binding patterns: (1) leukemic-specific, enriched in molecular functions such as tyrosine kinase signaling related to the Flt3-ITD mutation; (2) common to leukemia and myeloid progenitors; and (3) normal-specific. Here, KMT2A is linked to leukemia.