In the unselected breast cancer cohort (patients unselected for the family history and age at disease onset), additional twenty RAD52 delins carriers were identified (20/1983, 1.0%, P = 0.85, OR = 1.13, 95% CI = 0.54–2.36), but this frequency remained similar to that in controls (0.9%). This evidence concerns the gene RAD52 and breast cancer.