Dx: No primary given; DDx: CHF, liver disease, kidney disease, autoimmune or connective tissue disease; workup suggested: echocardiogram, abdominal ultrasonography (including kidney), viral hepatitis serology, autoimmune liver markers, drugs review, urinalysis, urine ratio of protein to creatinine, ANA, ANCA, complement levels. The gene discussed is BTG3; the disease is connective tissue disorder.