According to the results of the KEGG pathway enrichment, it is mostly linked to ECM-receptor interaction, Small cell lung cancer, Focal adhesion, Human papillomavirus infection, PI3K-Akt signaling pathway, Toxoplasmosis, Amoebiasis, Arrhythmogenic right ventricular cardiomyopathy and Hypertrophic cardiomyopathy (Figure 7D) (Supplementary Table S2). Here, AKT1 is linked to human papilloma virus infection.