HSD11B1 and skin basal cell carcinoma: 7-keto-cholesterol (7k-C), a precursor of 7k,27-OHC and 7β,27-DHC that can be catabolized to 7-hydroxycholesterol (7-OHC) by the oxysterol synthase Hsd11β124, was also enriched in BCC compared to adjacent skin, suggesting that the Hh target gene Hsd11β1 from NIH3T3 cells (Fig. 1g, h and Supplemental Table 3) may be suppressed in BCC.