This high percentage may be due, in part, to rare uncorrected C>U DNA editing events catalyzed by enzymes such as APOBEC3A/G and AID (activation-induced cytidine deaminase).8,10 APOBEC3A was already known to extensively edit DNA in neoplasms, which lends credence to this theory.10 Interestingly, neoplasms were only the sixth most common subject heading associated with editing sites predicted by RNAsee. The gene discussed is APOBEC3A; the disease is neoplasm.