GHRL and Alzheimer disease: This reduction in craving seems to confirm the prevailing hypothesis of the work that ectopic bacteria from the oral cavity to the gut contribute to the pathological state, because low red blood cell counts and hemoglobin content represent the poor state of nutrition in AD, and impaired nutritional status often with lower levels of ghrelin and alcohol craving, and consumed high quantity of ultra-processed food had higher obsessive thoughts about alcohol (Addolorato et al., 2006; Amadieu et al., 2021).