3β-Hydroxycholest-5-en-26-oic acid and stearic acid showed up-regulation in the SCC group, but aconitic acid,behenic acid,and glucose-6-phosphate were down-regulated (Table S3).Furthermore, the differential metabolites in ADC patients relative to SCC are mainly involved in ABC transporters and carbon metabolism in cancer is closely related (Figure S3C). This evidence concerns the gene ABCG2 and AIDS dementia complex.