For instance, significantly higher levels of IL-6 were detected in children with H1N1 virus infection, and the upregulation of IL-6 likely plays a proinflammatory role in H1N1 virus infection, which might be the crucial factor for airway inflammation and bronchial hyperreactivity in these children (Chiaretti et al., 2013; Zhao et al., 2021). The gene discussed is IL6; the disease is swine influenza.