Another case received chemotherapy based on comprehensive treatment.<h4>Results</h4>According to the pathological and immunohistochemical results, three cases were acinar adenocarcinoma of the prostate with Gleason score of 9, and all cases were PSA positive and negative for cytokeratin 7 (CK7) and GATA binding protein 3 (GATA-3). Here, GATA3 is linked to prostatic acinar adenocarcinoma.