As shown in Table 1, the univariate statistics showed that in the NSCLC combined with COPD group and the NSCLC group, gender, age, BMI, smoking index, treatment method, survival status, clinical symptoms 1, clinical symptoms 2, clinical symptoms 6, clinical symptoms 8, FEV1, FEV1/Pred, FEV1/FVC, RV/TLC, DLCO, Goddard score, E, EI, intact side emphysema ratio, affected side emphysema ratio, CA125, SCC, CYFRA21-1, Gran, CRP, TNM, cancer type, pathological location, significant P<0.05 for the above characteristics, as suspected factors. This evidence concerns the gene CRP and chronic obstructive pulmonary disease.