And the activated YAP further phosphorylates protein kinase B (AKT) and reduces glycogen synthase kinase‐3 β (GSK3β) activity, ultimately causing overexpression of forkhead box M1 (FOXM1) in cardiomyocytes and leading to myocardial fibrosis.133. The gene discussed is YAP1; the disease is Myocardial fibrosis.