The cell cycle‐regulated kinase aurora kinase A (AURKA) has been reported to interact directly with AXIN, disrupt the AXIN/GSK3β/β‐catenin complex, and stabilize β‐catenin, thus activating Wnt signaling to promote the self‐renewal of glioma‐initiating cells.109. This evidence concerns the gene AXIN1 and central nervous system cancer.