Recently, with the remarkable development of cancer research, extensive findings have indicated that caveolin-1 is a key factor in the occurrence, progression and prognosis of tumor (Witkiewicz et al., 2009a; Doherty and McMahon, 2009; Nassar et al., 2013; Chanvorachote et al., 2014; Li et al., 2018; Maiuthed et al., 2018). This evidence concerns the gene CAV1 and neoplasm.