For example, Hill et al. explored the important role of caveolin formation (Hill et al., 2008), Sunaga et al. introduced the opposite effects of caveolin-1 on the progression of non-small cell lung cancer and small cell lung cancer (Sunaga et al., 2004), and Williams et al. summarized the functions of caveolin-1 in cancer migration and metastasis (Williams and Lisanti, 2005). This evidence concerns the gene CAV1 and small cell lung carcinoma.