TRPV6 and cancer: For example, in both cell lines, where TRPV6 expression is altered, gene clusters associated with focal adhesion (KEGG: 04510), actin cytoskeleton regulation (KEGG: 04810), and ECM–receptor interaction (KEGG: 04512) are found in 10 functional clusters of genes that have been deregulated, indicating the transcriptional role of TRPV6 in cancer aggressiveness.