TGFB1 and metabolic dysfunction-associated steatohepatitis: Ohara et al. [45] revealed that extracellular vesicles (EVs) derived from adipose MSCs reduced the mRNA expression levels of the inflammatory cytokines such as TGF-β, TNF-α, IL-1β, and IL-6 in the livers of rats with nonalcoholic steatohepatitis.