Ohara et al. [45] revealed that extracellular vesicles (EVs) derived from adipose MSCs reduced the mRNA expression levels of the inflammatory cytokines such as TGF-β, TNF-α, IL-1β, and IL-6 in the livers of rats with nonalcoholic steatohepatitis. This evidence concerns the gene IL6 and metabolic dysfunction-associated steatohepatitis.