Memory B cells are key players in adaptive immunity and can proliferate and differentiate into plasma cells when stimulated by T effector cells or strong BCR stimulation.43 Previous research has shown that B cells can induce anti-tumor immunity and produce antibodies by acting as antigen-presenting cells.44 However, our findings indicated a decrease in the infiltration of monocyte, dendritic cell, and mast cell infiltrates involved in anti-tumor and antigen presentation. The gene discussed is BCR; the disease is neoplasm.