In view of the above finding that GINS1 enhances the survival of doxorubicin-challenged cells and the observation that GINS1 was regulated by FOXP1 and that both FOXP1 and GINS1 were positively correlated with poor prognosis of DLBCL, we next investigated whether upstream FOXP1 also contributed to DOX chemoresistance in DLBCL. Here, GINS1 is linked to diffuse large B-cell lymphoma.