TRPM2 and ischemic stroke: Given the potential link between the Ca2+/ROS system and TRPM2 on the one hand and NMDAR-mediated ischemic stroke on the other, the role of TRPM2 in ischemic stroke has been investigated in detail (Turlova et al., 2018; Zong et al., 2022a; Xu et al., 2022).