SFTPB and medical procedure: Only propofol reduced SP-B mRNA expression in alveolar epithelial cells in agreement with a previous in vivo study in an endotoxin-induced acute lung injury model in rats (48), in which the administration of propofol was associated with a decrease of SP-B mRNA in the lungs, and animals exposed to sevoflurane presented higher mRNA expression of SP-B, better lung oxygenation and reduced lung injury, compared to propofol (48).