The study by Wang Shaohua, the only author from China, focused on prevention and treatment strategies for DACD, has explored the association between serum uric acid levels (Huang et al., 2019), lipoprotein-associated phospholipase A2 (Cai et al., 2017), serum IGF-1/IGFBP-3 molar ratio decreased (Huang et al., 2015) and cognitive functions in T2DM patients. This evidence concerns the gene IGFBP3 and type 2 diabetes mellitus.