CEACAM5 and gastritis: We performed ROC analyses on 130 GC patients and 48 gastritis patients and found that the AUC of tRF-27-FDXXE6XRK45 was 0.762 (95% CI 0.684-0.839), which was higher than that of CEA 0.672 (95% CI 0.581-0.764), CA199 0.631 (95% CI 0.540-0.722) and CA724 0.715 (95% CI 0.635-0.795) (Fig. 5G).