Besides its role in immune cells, NR2F6 is upregulated in various human cancer cells, such as cervical cancer (69), ovarian cancer (71, 74), colon carcinoma (36), leukemia (33, 35), lung cancer (70), breast cancer (37), and hepatocellular cancer (75), indicating that NR2F6 is involved in tumor promotion and progression. This evidence concerns the gene NR2F6 and hepatocellular carcinoma.