Molecular docking results further confirmed that the major components in FHB bind to these key protein targets, with luteolin, wogonin, and quercetin having the highest binding energy to STAT3, implying that FHB may suppress the JAK-STAT pathway by binding to STAT3 to inhibit STAT3’s expression or/and phosphorylation, hence curing vitiligo. Here, SOAT1 is linked to vitiligo.