From the WB results of lesioned skin, the expression of P-STAT3 in the lesioned area was significantly reduced in the FHB-treated group (Figures 9E, F), which was consistent with the previous PCR results, FHB can inhibit the development of vitiligo by suppressing transcription factors upstream and downstream of the JAK-STAT pathway. The gene discussed is SOAT1; the disease is vitiligo.