Furthermore, GO and KEGG pathway analysis revealed that FHB may engage HIF-1, NF-kappaB, JAK-STAT, and other pathways to suppress the development of vitiligo, and has effects on “cytokine receptor binding”, “cytokine activity”, “nuclear receptor activity” and so on, which is closely related to the reported pathogenesis of vitiligo (41–44). The gene discussed is SOAT1; the disease is vitiligo.