CD8A and cancer: Given that Tissierella demonstrated a positive correlation with immune infiltration levels of CD8+ T cells and TAM1 cells (Additional file 4: Fig. S4), and was more abundant in TP53 wild type than TP53 mutant (Median 11.2 vs. 11.1, p = 0.019, Fig. 6E), we further examined its expression in pan-cancer and its prognostic significance.