The percentages of myeloid-derived suppressor cells (MDSCs; CD11b + Gr1 +) and macrophages (CD11b + F4/80) were significantly increased in the LowAhR and LowAhR + AD groups compared to the control group but significantly decreased in the LowAhR + AD + BJ group compared to the LowAhR + AD group (Fig. 6B, C). Here, ITGAM is linked to Alzheimer disease.