SHBG and autism: In post hoc analyses, BMI demonstrated a statistically significant inverse relationship with SHBG levels in crude and adjusted models for the overall cohort (β = − 10.35, p = 0.002; β = − 12.02, p < 0.001, respectively) and among those without autism (β = − 22.45, p < 0.001; β = − 24.22, p < 0.001, respectively).