We therefore screened for a panel of chemokines in sera of PpardTG mice and sex- and age-matched WT littermates at ages of 10 weeks (before GC development), 25 weeks (at early stages of GC, i.e., hyperplasia and low-grade dysplasia) and 55 weeks (at late stages of GC, i.e., high-grade dysplasia and adenocarcinoma) [8] using the LEGENDplex Mouse Proinflammatory Chemokine Panel, which simultaneously quantifies 13 major inflammatory chemokines (Ccl2, Ccl3, Ccl4, Ccl5, Ccl11, Ccl17, Ccl20, Ccl22, Cxcl1, Cxcl5, Cxcl9, Cxcl10, and Cxcl13). The gene discussed is CCL2; the disease is adenocarcinoma.