CCL22 and neoplasm: To further explore the clinical significance of these tested chemokines, we retrieved and analyzed the dataset GSE63089/GPL5175 using the NCBI GEO2R tool [26] and found that GC tissues had significantly higher mRNA expression of CCL20, CXCL1, CXCL5, CXCL9 and CXCL10 than those in their adjacent normal gastric tissues, but there was no significant difference in CCL2-5, CCL11, CCL22, CXCL13, and CCL17 between gastric normal and tumor tissues (Fig. 7a, b).