PDX1 and pancreatic neoplasm: As our tumor cell models, we have employed the commonly used cell line Panc02 (Corbett et al. 1984), a model established by the direct exposure into the pancreas of C57BL/6 mice with 3-methyl-cholanthrene, and the cell line UN-KC-6141, derived from the pancreatic tumor of a KrasG12D; Pdx1-Cre (KC) mouse (Torres et al. 2013).