As shown in Figure 4d–f, hormone-sensitive lipase (HSL) and acyl coenzyme A oxidase (ACOX) expression in the HF-LP group increased slowly, indicating that high-fat feeding was unable to metabolize the remaining fat in a timely manner; in contrast, ACOX and peroxisome proliferator-activated receptor α (PPAR-α) expression was significantly elevated after HF-HP diet intervention (p < 0.01), in line with the trend observed in the CON group. This evidence concerns the gene ACOX1 and hydrops fetalis.