ACE2 and COVID-19: Their active components, such as epigallocatechin 3-gallate (EGCG) and myricetin (Figure 1), have drawn considerable attention as potential agents for COVID-19 treatment owing to their multitargeting potential (SARS-CoV-2 Mpro, angiotensin-converting enzyme 2 [ACE2, the primary target of SARS-CoV-2 in host cells], and RNA-dependent RNA polymerase [RdRp, an essential enzyme in RNA viruses, which is a key player driving the viral replication and transcription machinery], among other targets), broad-spectrum activities, and low toxicity [17,18].