Several genes, including CYP17A1, CYP11B2, HSD11B1, CYP11B1, and NR3C2, which are implicated in the control of hypertension, regulate the synthesis of steroid hormones, such as glucocorticoids, mineralocorticoids, androgens, and estrogens. The gene discussed is NR3C2; the disease is hypertensive disorder.