ABCG2 and cancer: Important metabolic pathways in the humerus, discerned between the RC and HMK groups, included aminoacyl-tRNA biosynthesis, ABC transporters, biosynthesis of amino acids, 2-oxocarboxylic acid metabolism, amino sugar and nucleotide sugar metabolism, biosynthesis of nucleotide sugars, protein digestion and absorption, purine metabolism, D-Amino acid metabolism, central carbon metabolism in cancer, valine leucine and isoleucine biosynthesis, mineral absorption, valine leucine and isoleucine degradation, and monobactam biosynthesis (Figure 7C).