JAK2 and nervous system disorder: Other targeted pathways reported for the effects of A. graveolens in neurological disorders include Nrf2 and NF-κB pathways; BDNF/ERK/mTOR (antidepressant); CNTF/CNTFRa/JAK2/STAT3 (cerebral blood flow decreases); and SIRT1/PGC-1a (obstructive sleep apnea).