TNF and intracerebral hemorrhage: The findings showed that DL-NBP significantly decreased neurological deficit scores and increased the diameter of collaterals (arteriogenic effect), while L-NBP inhibited the expression of tumor necrosis factor-alpha (TNF-α) and matrix metallopeptidase 9 (MMP-9), thereby reducing inflammatory reactions due to intracerebral hemorrhage [30,37,43,44].