CXCR3 and neuropathy: It is known that at the spinal cord level, CXCL10 enhances the amplitude of spontaneous excitatory postsynaptic current and increases NMDA-/AMPA-induced currents via CXCR3; these results support a role for the CXCL10/CXCR3 axis in facilitating excitatory synaptic transmission in neuropathy [163].