The role of CXCL10 in nociceptive transmission seems to be very important since numerous studies have described its role in this process: its spinal upregulation has already been proven in many animal models, e.g., SNL-, CCI-, CIBP-, and STZ-evoked neuropathy [28,35,36,68,163,164]. The gene discussed is CXCL10; the disease is neuropathy.