CCL2 and neuropathy: CCR1 seems to be one of the most important receptors involved in neuropathy because it is a target of several chemokines that have been revealed to possess strong pronociceptive properties in studies performed on rodents, such as CCL2, CCL3, CCL4, CCL5, CCL7, CCL8, and CCL9 [15,16,17,19,20], and CCL6 is still poorly studied for its role in nociceptive transmission.