NFE2L2 and fatty liver disease: Quercetin also reduces hepatic steatosis through its antioxidant and anti-inflammatory activities, the inhibition of cell proliferation and apoptosis, and the inhibition of hepatic inflammatory responses through NF-κB and TLR inhibition, as well as the reduction of oxidative stress mediated by phosphatidylinositol 3-kinase/nuclear factor erythroid 2-related factor 2 (PI3k/Nrf2) [45].