PTGS2 and metabolic dysfunction-associated steatotic liver disease: Quercetin significantly increased anti-glutathione peroxidase four (GPX4) protein expression and decreased anti-cyclooxygenase 2 (COX2) and acyl-coenzyme A synthase long-chain family member four (ACSL4) protein expression, which suggests quercetin inhibits iron sagging in hepatocytes, as was demonstrated in NAFLD mice [46].