Venom peptide (Tv1) treatment in HCC cell line 1’s MEP cells resulted in a significant reduction in COX-2 and prostaglandin E2 (PGE2) levels, which was found to be associated with TRPV6/TRPC6-mediated calcium-dependent apoptosis [40]. The gene discussed is TRPV6; the disease is hepatocellular carcinoma.