MiR-137 has been shown to inhibit tau hyperphosphorylation via its actions with the 3′-UTR of the calcium voltage-gated channel subunit alpha-1 C (CACNA1C) mRNA, suppressing expression of its protein product in the hippocampus and cortex of AD mice, which is presumably involved in tau hyperphosphorylation [157]. This evidence concerns the gene MAPT and Alzheimer disease.