Several lncRNAs, including BACE1-AS, MALAT1, 51A, 17A, NDM29, BC200, NAT-Rad18, and BDNF-AS are known to regulate APP processing, tau phosphorylation, synaptic plasticity, and neuroinflammation and have been shown to play varying roles in AD pathogenesis [210]. Here, APP is linked to Alzheimer disease.