The control samples had the lowest median value (66.15 pg/mL), and the concentration of plasma IL-23 was gradually higher in CHC-SF and CHC-NSF (median values were 88.72 pg/mL and 92.64 pg/mL, respectively), and finally, patients with NASH had the highest plasma concentrations of IL-23 (131.80 pg/mL). This evidence concerns the gene IL37 and metabolic dysfunction-associated steatohepatitis.